Normal CD4+ T lymphocyte levels in HIV seronegative individuals in the Manya/Yilo Krobo communities in the Eastern region of Ghana.
Identifieur interne : 000D54 ( Main/Exploration ); précédent : 000D53; suivant : 000D55Normal CD4+ T lymphocyte levels in HIV seronegative individuals in the Manya/Yilo Krobo communities in the Eastern region of Ghana.
Auteurs : William Ampofo [Ghana] ; Kwasi Torpey ; Y D Mukadi ; Kwadwo Koram ; Kisten Nolan ; Richard Amenyah ; Ekow Kaitoo ; Phyllis Antwi ; David Ofori-Adjei ; Peter LampteySource :
- Viral immunology [ 0882-8245 ] ; 2006.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Femelle, Ghana, Humains, Lymphocytes T CD4+ (immunologie), Mâle, Numération des lymphocytes CD4 (normes), Organisation mondiale de la santé, Rapport CD4-CD8, Répartition par sexe, Sujet âgé, Sujet âgé de 80 ans ou plus, Séronégativité VIH (immunologie), Valeurs de référence.
- MESH :
- immunologie : Lymphocytes T CD4+, Séronégativité VIH.
- normes : Numération des lymphocytes CD4.
- Adolescent, Adulte, Adulte d'âge moyen, Femelle, Ghana, Humains, Mâle, Organisation mondiale de la santé, Rapport CD4-CD8, Répartition par sexe, Sujet âgé, Sujet âgé de 80 ans ou plus, Valeurs de référence.
- Wicri :
- geographic : Ghana.
English descriptors
- KwdEn :
- MESH :
- geographic : Ghana.
- immunology : CD4-Positive T-Lymphocytes, HIV Seronegativity.
- standards : CD4 Lymphocyte Count.
- Adolescent, Adult, Aged, Aged, 80 and over, CD4-CD8 Ratio, Female, Humans, Male, Middle Aged, Reference Values, Sex Distribution, World Health Organization.
Abstract
The goal of this study was to determine the normal levels of CD4+ T lymphocytes in healthy individuals who were HIV seronegative in the Manya and Yilo Krobo Districts of Ghana's Eastern Region. This enabled comparisons with normal CD4 count ranges established by the World Health Organization (WHO). The study population consisted of 249 HIV-seronegative clients from a mobile free Voluntary Counseling and Testing (VCT) service in communities of the two districts during a one-month period. The mean CD4 count of these individuals was 1067 cells/microl with women demonstrating higher baseline CD4 counts than men. This study found a WHO comparable HIV seronegative baseline CD4 count as well as gender-based differences in the CD4 count and CD4/CD8 ratio. Establishment of the adult baseline for the country provides important demographic data and indicates the appropriateness of current global treatment guidelines with regards to CD4 levels in Ghana.
DOI: 10.1089/vim.2006.19.260
PubMed: 16817768
Affiliations:
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Le document en format XML
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Values</term><term>Sex Distribution</term><term>World Health Organization</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Ghana</term><term>Humains</term><term>Mâle</term><term>Organisation mondiale de la santé</term><term>Rapport CD4-CD8</term><term>Répartition par sexe</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Valeurs de référence</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Ghana</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The goal of this study was to determine the normal levels of CD4+ T lymphocytes in healthy individuals who were HIV seronegative in the Manya and Yilo Krobo Districts of Ghana's Eastern Region. This enabled comparisons with normal CD4 count ranges established by the World Health Organization (WHO). The study population consisted of 249 HIV-seronegative clients from a mobile free Voluntary Counseling and Testing (VCT) service in communities of the two districts during a one-month period. The mean CD4 count of these individuals was 1067 cells/microl with women demonstrating higher baseline CD4 counts than men. This study found a WHO comparable HIV seronegative baseline CD4 count as well as gender-based differences in the CD4 count and CD4/CD8 ratio. Establishment of the adult baseline for the country provides important demographic data and indicates the appropriateness of current global treatment guidelines with regards to CD4 levels in Ghana.</div></front></TEI><affiliations><list><country><li>Ghana</li></country></list><tree><noCountry><name sortKey="Amenyah, Richard" sort="Amenyah, Richard" uniqKey="Amenyah R" first="Richard" last="Amenyah">Richard Amenyah</name><name sortKey="Antwi, Phyllis" sort="Antwi, Phyllis" uniqKey="Antwi P" first="Phyllis" last="Antwi">Phyllis Antwi</name><name sortKey="Kaitoo, Ekow" sort="Kaitoo, Ekow" uniqKey="Kaitoo E" first="Ekow" last="Kaitoo">Ekow Kaitoo</name><name sortKey="Koram, Kwadwo" sort="Koram, Kwadwo" uniqKey="Koram K" first="Kwadwo" last="Koram">Kwadwo Koram</name><name sortKey="Lamptey, Peter" sort="Lamptey, Peter" uniqKey="Lamptey P" first="Peter" last="Lamptey">Peter Lamptey</name><name sortKey="Mukadi, Y D" sort="Mukadi, Y D" uniqKey="Mukadi Y" first="Y D" last="Mukadi">Y D Mukadi</name><name sortKey="Nolan, Kisten" sort="Nolan, Kisten" uniqKey="Nolan K" first="Kisten" last="Nolan">Kisten Nolan</name><name sortKey="Ofori Adjei, David" sort="Ofori Adjei, David" uniqKey="Ofori Adjei D" first="David" last="Ofori-Adjei">David Ofori-Adjei</name><name sortKey="Torpey, Kwasi" sort="Torpey, Kwasi" uniqKey="Torpey K" first="Kwasi" last="Torpey">Kwasi Torpey</name></noCountry><country name="Ghana"><noRegion><name sortKey="Ampofo, William" sort="Ampofo, William" uniqKey="Ampofo W" first="William" last="Ampofo">William Ampofo</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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